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gestational path

gestational and placental path

Abruptio placentae premature separation of the placenta; important cause of antepartum bleeding and fetal death; often associated with DIC
placenta accreta attachment of placenta directly to myometrium
placenta accreta the dicidual layer is defective, is predisposed by endometrial inflammation and old scars
placenta accreta manifests clinically by impaired placental separation oafter delivery, sometimes with massice hemorrhage
placenta previa an attachment of the placenta to the lower uterine segment, may partially or sompletely cover cervical os
placenta previa may coexist with placenta accreta, often manifests with bleeding
ectopic pregnancy most often occurs in fallopian tubes but can also occur in the ovary, abdominal cavity or cervix
ectopic pregnancy most frequently predisposed by salpingitis(often gonorrgeal) but also predisposed by endometriosis and postoperative adhesions
ectopic pregnancy most common cause of hematosalpinx, may lead to tubal rupture
toxemia of pregnancy characterized by severe HTN, occurs in the third trimester and most often during the first pregnancy, affects kidneys liver and CNS
tidiform mole manifests by enlarged, edematous placental villi in a loose stroma (bunch of grapes)
hydatidiform mole causes a significant increase in hCG, characterized by vaginal bleeding and rapid increase in uterine size
complete mole no embryo present, 46xx karyotype of exclusively paternal derivation
partial mole embryo present, triploidy or tetraploidy, due to fertilization by two sperm
gestational choriocarcinoma aggressive malignant neoplasm, increased serum hCG, early hematogenous spred to lungs, is responsive to chemo
gestational choriocarcinoma is preceded by--> hydatidiform mole(50%), abortion of ectopic pregnancy(20%), normal term pregnancy (20-30%)
Created by: swohlers