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OPT Soft Tiss Tumors

TermDefinition
fibroma most common tumor-like lesion of the oral cavity; really a reactive hyperplasia of CT, not a true neoplasm
giant cell fibroma fibrous CT nodule with large stellate fibroblasts; occurs in first 3 decades of life
retrocuspid papilla small, raised lesion on attached gingiva lingual to the lower canines; usually disappear with age
epulis fissuratum tumor-like proliferation of fibrous CT that develops in association with ill-fitting denture
fibroepithelial polyp (leaflike denture fibroma) flattened pink mass on hard palate attached by narrow stalk
inflammatory papillary hyperplasia reactive tissue growth on hard palate beneath maxillary denture
fibromatoses group of true fibrous neoplasm with biologic behavior between benign and malignant -can reach considerable size so pt should be evaluated for Gardner's
juvenile aggressive fibromatosis fibromatoses on head and neck tissues
desmoplastic fibromas fibromatoses in head and neck within the bone; true neoplasm of myofibroblasts
myofibroma less infiltrative tumor of myofibroblasts
fibrous histiocytoma/dermatofibroma, solitary fibrous tumor, and oral focal mucinosis less aggressive fibrous tumors, sessile painless growths that do not tend to recur
pyogenic granuloma common reactive tumor-like proliferation of granulation tissue in response to irritation; red/purple painless and pedunculate mass with ulcerative surface, often on gingiva and can evolve into inflammatory fibrous hyperplasia
pregnancy tumors / granuloma gravidarum gingival pyogenic granulomas that occur during pregnancy
epulis granulomatosa hyperplastic granulation tissue growing out of a healing tooth socket
peripheral giant cell granuloma tumor-like proliferation of osteoclastic giant cells in response to irritation; reddish-blue to purple sessile or pedunculate mass on gingiva or edentulous ridge
peripheral ossifying fibroma reactive lesion from PDL of fibrous CT, osteoblasts and mineralized tissue; red or pink nodules on gingiva or alveolar ridge
lipoma benign tumor of adipose tissue commonly in subcutaneous buccal mucosa; yellow color if superficial
fibrolipoma lipoma with significant amount of fibrous CT
angiolipoma lipoma with numerous small blood vessels
spindle cell lipomas lipoma with myxoid storm and increased cellularity
traumatic neuroma not true neoplasm, reactive proliferation of nerve tissue after it has been severed/damaged
schwannoma benign encapsulated neural tumor from Schwann cells that contains Verocay bodies, 45% in the head and neck
neurofibromatosis 2 disease with bilateral schwannomas of auditory-vestibular nerve (acoustic neuroma) and cafe-au-lait pigmentations -{gene on chromosome 22}
schwannomatosis hereditary disease of multifocal schwannomas
Verocay bodies seen in Antoni A tissue; Schwann cells arranged in palisading fashion around central acellular zones
neurofibroma most common peripheral nerve tumor that arises from Schwann cells, fibroblasts and neurites
neurofibromatosis 1 autosomal dominant disorder caused by mutations of {NF1 gene on chromosome 17} that affects the tumor suppressor protein {neurofibromin}; variable expressivity of neurofibromas and enlargement of fungiform papilla seen in mouth
elephantiasis neuromatosa large pendulous masses of neurofibromas on the skin
cafe-au-lait spots smooth-edged tan/brown pigmentations on skin; associated with {neurofibromatosis 1}
Lisch nodules brown spots on the iris of the eye, associated with {neurofibromatosis 1)
Crowe sign freckling of the axilla, seen with {neurofibromatosis 1}
multiple endocrine neoplasia rare group of neuroendocrine tumors
MEN type 2B arises from mutation of {RET oncogene} on chromosome 10, oral neuromas are an early sign; marfanoid habitus, pheochromocytomas and medullary carcinoma
melanocytes neuroectodermal tumor of infancy rare pigmented tumor from neural crest cells; pathoses arise in anterior maxilla as black/blue mass
granular cell tumor benign soft tissue tumor of unknown origin, pink to yellow mass on dorsum of tongue
congenital epulis rare soft tissue tumor on alveolar ridge of newborns likely from fibroblasts; 90% in females and the maxilla
hemangiomas proliferation of endothelial cells and vascular lumina; most common tumor of infancy, resolves spontaneously
capillary hemangioma hemangioma of small capillaries
cavernous hemangioma hemangioma of dilated vascular spaces
vascular malformations overgrowths of blood vessels without endothelial proliferations; persist through life
venous malformations low-flow vascular malformations
arteriovenous malformations high-flow vascular malformations
port wine stain (nevus flammeus) superficial capillary angiomas of the face, follow trigeminal nerve; associated with {Sturge-Weber angiomatosis}
Sturge-Weber angiomatosis non-hereditary developmental condition of multiple angiomas of the brain and face
gyriform/tramline calcification leptomeningeal angiomas that calcify and show up on skull films as loops
nasopharyngeal angiofibroma tumor of vascular and fibrous CT, almost exclusively in males; destructive growth in nasopharynx
lymphangioma benign, hamartomatous growth of lymphatic vessels; probably a developmental abnormality
cystic hygroma lymphangioma with large cystic spaces
leiomyoma benign tumor of smooth muscles; often in uterus and GIT
vascular leiomyoma (angiomyoma, angioleiomyoma) leiomyomas with thick-walled blood vessels and bluish hue
fibrosarcoma malignant tumor of fibrous CT, usually low-grade
liposarcoma malignant tumor of adipose tissue
neurofibrosarcoma malignancy of peripheral nerves, very aggressive with early metasasis
angiosarcoma malignant vascular tumor from endothelial cells lining blood vessels
leiomyosarcoma malignant tumor of smooth muscle, aggressive with early metastasis
Kaposi sarcoma arises from vascular endothelium and in multiple sites as once; triggered by HHV-8
rhabdomyosarcoma malignant tumor of skeletal muscle, most common in children
Created by: Alexandra Arnold Alexandra Arnold