click below
click below
Normal Size Small Size show me how
CM Stroke Mngment
Stroke Management
| Question | Answer |
|---|---|
| Stroke Risk Factors | older age (every decade over age 55, risk doubles), men (more women die from stroke), AA, hispanic, obesity, alcohol abuse, smoking, poor diet/nutrition |
| Modifiable risk factors | HTN, atrial fib, carotid stenosis, diabetes, hyperlipidemia, prior stroke, TIA |
| How much can weight reduction lower bp? | up to 20mmHG/10kg weight loss |
| Single most treatale risk factor for stroke | High bp |
| What percentage Risk Reduction is acheivable with aspirin? | 22% |
| Warfarin vs Aspirin | Warfarin has better risk reduction (45%). |
| CHADS pneumonic | CHF, HTN, Age >75, Diabetes, Stroke of TIA. (6 possible points. 3 is high treat with warfarin. Moderate =2 points, can argue either way with warfarin. Below 2, treat with aspirin) |
| If CHADs score is 2 from previous stroke, tx with | Warfarin. |
| % stenosis = 1- (A/B), what is A? | A is the area of tightest narrowing. B is the normal width |
| What is the impact of tight glucose control on macrovascular complications? | none. Macrovascular complications not affected by glucose control. Tight control of HTN is the goal. |
| Cholesterol and RR | No evidence that lowering cholesterol overall affects stroke incidence. But if you use statins in patients with CHD, there is a risk reduction |
| Aspirin in low-risk pts | no data to support using Aspirin. Risk outweighs benefit (bleeds). Aspirin recommended for 10-yr cardiovascular risk 6-10% |
| Only FDA approved therapy for pts with acute stroke | IV-tPA (clot busting drug) |
| What is the protocol for giving tPA | initiated within 3 hours of sx onset (taken from the last time the pt was known to be sx free). Head CT without evidence of hemorrhage or other complicating lesion |
| What are pts treated with if they are not candidates for receiving tPA? | endovascular - catheter, remove clot mechanically |
| MERCI clot retriever | Used to remove clots |
| Acute stroke management | Temperature, Fluids/Glucose, BP, Antithrombotic agents |
| Cerebral Blood flow equation | MAP/CVR; if you stand, MAP decreases, so CVR accomodates this by decreasing/dilating in order to keep CBF constant. |
| In stroke patients, CVR is | constant. If MAP is decreased, then CBF decreases; there is some data to suggest that tx of antihypertensives in acute pts can be harmful. So don't treat high bp acutely |
| Only data available on anticoagulation in acute pts is on which drug | Aspirin (when started within 48 hours) decreases recurrent events up front. Need to treat 100 pts to decrease 1 stroke |
| 3 top complications in stroke patients | UTI (11%), CHF (10% - watch fluids!), Pneumonia (10%) |
| DVT prophylaxis | given to all stroke patients who can't get up and walk. DVT risk is 2% |
| Secondary Prevention | Platelet antiaggregants, anticoagulants, blood pressure, lipid lowering, endarterectomy |
| Prior stroke patients treated with Warfarin have what type of Risk Reduction? | 67% decrease in risk when treated with Warfarin |
| Each 10mmHg decrease in systolic BP is associated with _____% decrease in stroke risk? | 28%. Do not use acutely |
| Motor recovery after stroke is determined by | the severity of the stroke |