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FSHN 450-3 Trsplants

Autologous bone marrow or stem cells from host
Allogenic bone marrow/stem cells or organ from donor
Xenogenic organ from different species (ethical/rejection issues)
Humoral response antibodies
Cell-mediated response T-cells
5 mechanisms of anti-rejection drugs purine synthesis, inhibit cytokine production, inhibit binding, inhibit T-cell activation, suppress T-cell maturation or proliferation
organ matching blood type, antibodies, MHC
what juice to avoid with immunosuppressive drugs? grapefruit
cardiac cachexia hypermetabolic, congestion/edema, eating increases O2 req
LVAD left ventricular assist device (increases QOL when waiting for heart/lung transplant)
Primary biliary cirrhosis immune system attacks bile ducts
Sclerosing cholangitis scarring and narrowing of bile ducts inside and outside of liver
Biliary atresia malformation of the bile ducts
Wilson’s disease abnormal levels of copper in liver
Hemochromatosis accumulation of iron in liver
Vascular anastomosis connecting vasculature during transplants
Protein kidney/liver vs. others less to not ruin new organs
Created by: melaniebeale