CLOZAPINE(CLAZARIL)USED AS A LAST RESORT FOR PEOPLE WITH RETRACTABLE PSYCHOSIS.S/E DROWSINESS, SEDATION, DIZZINESS, TACHYCARDIAPOSS FATAL S/EAGRANULOCYTOSIS, CONVULSIONS, NEUTROPHILS < 2000/ABSOL NEUTROPHILS <1000 D/C PERM
MOOD STABILIZERS
LITHIUM, TEGRETOL(carbamazepine), DEPAKOTE (divalproex), LAMICTAL (lamotrigine), NEURONTIN (gabapentin), TOPAMAX (topiramate), KLONOPIN (CLONAZEPAM)**USED FOR BIPOLAR, MOOD CHANGES WITH MANIA AND PSYCOSIS
LITHIUM
MOST ESTABLISHED STABILIZER, NORMALIZES REUPTAKE OF NT, REDUCES RELEASE OF NOREPI, ACTION OCCURS INTRACELLULARLY INSTEAD OF AT SYNAPSE, REQUIRES SERUM MONITORING
LITHIUM
THEURAPEUTIC RANGE 0.6-1.2S/E: N/D ANOREXIA, FINE HND TREMOR, POLYURIA, POLYDIPSIA, METAL TASTE, FATIGUE, >WBC..LATER S/E: WGT GAIN, ACNE, ALOPECIA, COARSE TREMORS, CONFUSSION, SLURRED SPCH, SEDATION..EVENT LEADING TO: ARRITHYMIAS, SEIZURES, COMA, DEATH
LITHIUM TEACHING
COMPLIANCE, SERUM LEVELS, TAKE WITH FOOD, HYDRATION, Na INTAKE SHOULD STAY AT LEVEL AS WHEN MED WAS THERAPEUTIC.HAND TREMORS...HOLD LITHIUM
SEROTONIN
INHIBITS CATECHOLAMINE AND MEDIATES COGNITIVE EFFECTS, EMOTIONS DURING PANIC, MEMORY AND ANXIETY, VIOLENCE/AGGRESSION, SEXUAL FUNCTION, SLEEP/WAKE CYCLE
ANTIDEPRESSANTS TYPICAL/STANDARD
ELAVIL (amitriptyline), TOFRANIL (imipramine)req bld level, PAMELOR (nortriptyline) req bld levelANTICHOLINERGIC S/E, CARDIAC S/E1980'SOD=DEATHNEEDS TO BE TAPERED OFF
Ch.18 LTI-MA 509
