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Block 4
Genital System
| Question | Answer |
|---|---|
| What is the key to sexual dimorphism? | Y chromosome (SRY gene is the master gene that influences male development) |
| Gonads do not acquire male or female characteristics until when? | 7th week |
| Germ cells arrive in the gonadal ridges when? | 6th week |
| if the embryo is genetically male, the primitive sex cords continue to proliferate and penetrate deep into the medulla forming what? | Testis/medullary cords |
| Near the hilum, the medullary cords break up into thin stands that become what? | Rete testis |
| What is the dense layer of connective tissue that separates the medullary cords from the surface epithelium? | Tunica albuginea |
| In the 4th month the testis cords become horseshoe-shaped. The ends of the cord are continuous with what? | Rete testis |
| What influences differentiation of the genital ducts and external genitalia? | Testosterone |
| Testis cords are solid until puberty when they develop a lumen and become what? | Seminiferous tubules |
| The seminiferous tubules connect to what? | Rete testis |
| The rete testis connects to what? | Ductuli efferentes |
| Ductuli are derived from what? | Remaining excretory tubules of the mesonephros |
| The ductuli efferentes connects to what? | Wolffian duct (becomes the epididymis) |
| At the distal end of the ductus deferens develops an outpouching that becomes what? | Seminal vesicle |
| Where do the ducts of the male terminate? | Prostatic urethra |
| In the ovary the surface epithelium continues to proliferate forming cords called what? | Cortical cords |
| In females, longitudinal invagination of epithelium on the urogenital ridge forms what structure? | Paramesonephric (Mullerian) ducts |
| When the two paramesonephric (Mullerian) ducts fuse they form what structure? | Uterine canal |
| The caudal tip of the fused paramesonephric (Mullerian) ducts projects into the posterior wall of the urogenital sinus forming what? | Paramesonephric (Mullerian) tubercle |
| The paramesonephric ducts give rise to what structures? | Uterine tubes, uterus, and superior portion of the vagina |
| The upper part of the vagina is originated from what? | Paramesonephric ducts |
| The lower part of the vagina is originated from what? | Urogenital sinus |
| The lumen of the vagina is separated from the urogenital sinus by a thin plate of tissue called what? | The hymen |
| Slightly elevated folds that form around the cloaca by cells that migrate from the primitive streak are called what? | Cloacal folds |
| Cranial to the cloacal membrane the cloacal folds unite to form what? | Genital tubercle |
| Caudally the cloacal folds subdivide into the what to folds? | Urethral folds (anteriorly) and anal folds (posteriorly) |
| Lateral to the urethral folds, another pair of elevations form called what? | Genital swellings |
| In males the genital swellings become what? | Scrotum |
| In females the genital swellings become what? | Labia majora |
| The rapid elongation of the genital tubercle is called what? | Phallus |
| The phallus pulls the urethral folds forward forming what? | Urethral groove |
| The epithelial lining of the urethral groove forms what? | Urethral plate |
| At the end of the third month, the urethral folds close over forming what? | Penile urethra |
| Hoe is the distal portion of the urethra formed? | Ectodermal cells from the tip of the glans penetrate inward to form a short cord that forms a lumen that connects to the penile urethra. |
| The scrotal swellings arise in what region? | Inguinal region |
| A defect that exposes the urethra on the ventral surface of the penis is known as what? | Hyppspadia |
| Extrophy of the bladder is called what? | Epispadia |
| Genital tubercle elongates forming what? | Clitoris |
| The urethral folds do not fuse in females, instead they form what? | Labia minora |
| The urogenital groove in females stay open forming what? | Vestibule |
| The testes reach the inguinal region by when? | 12th week |
| When do the testes migrate through the inguinal canal? | 28 weeks |
| When do the testes reach the scrotum? | 33 weeks |
| Cryptoorchidism is associated with what? | Renal abnormalities |
| Ovaries descend to where? | Just below the rim of the true pelvis (lie posterior to the broad ligament) |