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Micro Exam #4

Laura's part (disease/pathogens/septic shock)

QuestionAnswer
normal flora microorganisms that colonize a person or animal without usually causing disease (either beneficial or no effect)
infection growth of pathogenic organisms in the body whether or not body function is impaired
disease impaired body function; any change from a state in health
communicable disease caused by a pathogen
noncommunicable disease caused by a genetic or degenerative process
opportunistic pathogens require special circumstances to produce disease; one will often cause a variety of infections; are commmonly encountered organisms or ones that you carry with you
true pathogens able to infect a healthy host under their own power to initiate disease; usually cause one specific disease; are not so commonly encountered and are not carried with you
adherence factors of a pathogen capsule, fimbriae, surface receptors, hook, viral spikes, use of host cell actin fibers to attach to and then enter the host cell (see pg. 51 for more detail)
collagenase virulence exoenzyme; dissolves collagen; softens up tissue so the infection can spread
hyaluronidase virulence exoenzyme; dissolves hyaluronic acid; helps infection to spread
exotoxins released from live bacteria; come from both Gram + and - bacteria; are proteins; more toxic (tiny amounts have a great effect); have specific effects; heat sensitive; antigenic (stimulate an immune response)
endotoxins are released from dead bacteria; come only from Gram - bacteria; are lipopolysaccharides; less toxic; more generalized effects; note heat sensitive; generally not antigenic; results in the blood: inflammation, low bp, fever, excess clotting, edema
toxoid a modified exotoxin used as a vaccine
local infection confined to one area of the body
systemic infection throughout the body (carried by the blood)
septic shock life threatening systemic response to a bacterial infection (usually caused by a Gram - organism, but other microorgansims can cause this)
symptoms of septic shock swelling (edema) of the face, hands, & feet; low bp and rapid, weak pulse; dyspnea (difficultly breathing); fever; disorientation, confusion, irritability, somnolence (sleepiness)
treatments for septic shock inject epinephrine; open airway (intubation or tracheostomy); oxygen if needed; restore blood volume with rapid intravenous infusion of isotonic solution; draw blood (blood gases and pathogen isolation); broad sprectrum bacteriostatic drug
Created by: lisaanne11
 

 



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