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development of back

where is neural tube and neural crest cell develope from? Epiblast-> ectoderm -> neura tube and neural crest cell
Neuroepithelial layer give rise to all spinal neurons and some support cell
Mantle layer form by neuroepithelial cell that divide and differentiate into neuroblast cells
Marginal layer region that will contain white matter + Meninges
Meninges layer of membrane that give rise to CNS
after thickening of neural tube, what does mantle layer differentiate into? 1) Alar plate (posterior horn) 2) Basal plate (anterior horn)
Alar plate formed from mantle layer, it formed posterior horn (sensory neuron)
Basal plate formed from mantle layer, it formed anterior horn (motor neuron)
Intermediate horm formed between posterior and anterior horns
where does motor and sensory neuron meet? spinal nerve
where does Posterior ramus innverate? Motor and sensory of dermomyotome of Back example: erretus and intrinsic muscle of back
Where does anteriro ramus innverate with? Motor and sensory of dermomyotome of body wall and limbs
Ramus vs Root Root contribute to ramus Root contain either sensory (posterior root) or motor (anterior root) neurons Ramus contains both motor and sensory
landmark of dermatome C3=neck, T4=nipple, T10=umbilical, L1-Inguinal line, C8=5th digit of hand, C6=Pollex, L4=knee, L5=anterior ankle and foot, S2=posterior lower limb
where does anterior ramus goes to? To the hypomere: skin (everywhere except midline of back) and to hypaxial (extrinsic0 muscle
Where does posterior ramus goes to? To the epimere: skin along the midline of back (to the coastal angle) and to epaxial (instrinsic) muscle
Hypomere skin (everywhere except midline of back) and to the hypaxial (extrinsic muscle) inneverated by anterior ramus
Epimere Skin along the midline of back (to the coastal angle) and to epaxial(intrinsic) muscle innverated by posterior ramus
Sclerotome resegmentation Sclerotome is resegnmented into upper and lower part, which then migrate to adjacent to allow nerve fiber transmission proces
what does sclerotomal mesenchyme give rise to? Vertebrae and Rib Sclerotomal mesenchyme ==> cartilage ==> bone
disease when spinous process is not form? Spina bifida
Name possible clinical disease associate with spina bifida 1) spina bifida occulta 2) meningocele (surgically removed) 3) meningomyelocele 4) Rachischisis (usually fatal)
After formation of vertebrate, what does notochord become? Nucleus pulposus
Which segment does T12 most assoicate with? Lower lumbar spinal cord segment
Which segment does L1 most assoicate with? All sacral spinal cord segment
Created by: powerbaby